Fact Checked by Doctor NameCannabis causes cottonmouth, or dry mouth, which is innocuous.
While high, most cannabis users suffer extreme tongue and throat dryness.
Cottonmouth is not hazardous and may be treated.
What Causes Cottonmouth?
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THC, the main psychoactive ingredient in marijuana, causes cottonmouth. THC activates salivary gland cannabinoid receptors.
This reduces saliva, causing transient dry mouth. Lack of saliva causes cottonmouth, which feels like cotton balls or fabric in your mouth.
THC causes cottonmouth by binding to cannabinoid receptors called CB1 receptors concentrated in certain parts of the brain.
This inhibits communication between the cannabinoid receptors and the salivary glands. With signals suppressed, the salivary glands reduce saliva output.
In addition to THC, other cannabinoids like CBD may contribute to cottonmouth based on their interactions with cannabinoid receptors.
The drying effect depends on the strain and dosage consumed. Higher THC strains are more likely to cause intense dry mouth.
Is Cottonmouth Dangerous?
While uncomfortable, cottonmouth itself is completely harmless, and there are no long-term effects.
A chronically dry mouth can lead to an increased risk of tooth decay or gum disease if proper oral hygiene is not maintained.
However, this level of dryness is more severe than occasional cannabis-related cottonmouth.
Cottonmouth should not harm your teeth or gums if you keep hydrated and brush regularly.
Keep your mouth moist before, during, and after cannabis use by drinking lots of water. OTC dry mouth sprays and lozenges may also help.
